@article {Bowler2008, title = {{The Phaeodactylum genome reveals the evolutionary history of diatom genomes}}, journal = {Nature}, volume = {456}, year = {2008}, pages = {239{\textendash}244}, abstract = {Diatoms are photosynthetic secondary endosymbionts found throughout marine and freshwater environments, and are believed to be responsible for around one- fifth of the primary productivity on Earth(1,2). The genome sequence of the marine centric diatom Thalassiosira pseudonana was recently reported, revealing a wealth of information about diatom biology(3-5). Here we report the complete genome sequence of the pennate diatom Phaeodactylum tricornutum and compare it with that of T. pseudonana to clarify evolutionary origins, functional significance and ubiquity of these features throughout diatoms. In spite of the fact that the pennate and centric lineages have only been diverging for 90 million years, their genome structures are dramatically different and a substantial fraction of genes (similar to 40\%) are not shared by these representatives of the two lineages. Analysis of molecular divergence compared with yeasts and metazoans reveals rapid rates of gene diversification in diatoms. Contributing factors include selective gene family expansions, differential losses and gains of genes and introns, and differential mobilization of transposable elements. Most significantly, we document the presence of hundreds of genes from bacteria. More than 300 of these gene transfers are found in both diatoms, attesting to their ancient origins, and many are likely to provide novel possibilities for metabolite management and for perception of environmental signals. These findings go a long way towards explaining the incredible diversity and success of the diatoms in contemporary oceans.}, issn = {0028-0836}, doi = {10.1038/nature07410}, url = {http://apps.isiknowledge.com/InboundService.do?Func=Frame\&product=WOS\&action=retrieve\&SrcApp=EndNote\&Init=Yes\&SrcAuth=ResearchSoft\&mode=FullRecord\&UT=WOS:000261039300040}, author = {Bowler, C and Allen, A E and Badger, J H and Grimwood, J and Jabbari, K and Kuo, A and Maheswari, U and Martens, C and Maumus, F and Otillar, R P and Rayko, E and Salamov, A and Vandepoele, K and Beszteri, B and Gruber, A and Heijde, M and Katinka, M and Mock, T and Valentin, K and Verret, F and Berges, J A and Brownlee, C and Cadoret, J-P and Chiovitti, A and Choi, C J and Coesel, S and De Martino, A and Detter, J C and Durkin, C and Falciatore, A and Fournet, J and Haruta, M and Huysman, M J J and Jenkins, B D and Jiroutova, K and Jorgensen, R E and Joubert, Y and Kaplan, A and Kroger, N and Kroth, P G and La Roche, J and Lindquist, E and Lommer, M and Martin-Jezequel, V and Pascal Jean Lopez and Lucas, S and Mangogna, M and McGinnis, K and Medlin, L K and Montsant, A and Oudot-Le Secq, M P and Napoli, C A and Obornik, M and Parker, M S and Petit, J L and Porcel, B M and Poulsen, N and Robison, M and Rychlewski, L and Rynearson, T A and Schmutz, J and Shapiro, H and Siaut, M and Stanley, M and Sussman, M R and Taylor, A R and Vardi, A and von Dassow, P and Vyverman, W and Willis, A and Wyrwicz, L S and Rokhsar, D S and Weissenbach, J and Armbrust, E V and Green, B R and Van De Peer, Y and Grigoriev, I V} }