@article {3514,
	title = {Effect of zinc sacrificial anode degradation on the defence system of the Pacific oyster, Crassostrea gigas: chronic and acute exposures.},
	journal = {Mar Pollut Bull},
	volume = {64},
	year = {2012},
	month = {2012 Sep},
	pages = {1911-20},
	abstract = {<p>Two types of exposures were performed to assess the effects of zinc released from sacrificial anode degradation: a chronic exposure, in which oysters were exposed to 0.53{\textpm}0.04 mg Zn L(-1) for 10 weeks, and an acute exposure, where oysters were exposed to 10.2{\textpm}1.2 mg Zn L(-1) for 1 week. At the end of the acute exposure experiment, 81.8\% mortality was recorded. In contrast, no mortality was detected after 10 weeks exposure. Moreover, all of the immune system biomarkers studied, except the number of circulating haemocytes, were stimulated by a moderate level of zinc and inhibited by a high level. Our exposure conditions did not induce SOD or MXR mRNA expression in gills and digestive gland. However, an increase of MT mRNA is observed in these tissues. The results indicate that oysters are sensitive to acute zinc toxicity but are only moderately affected by a mild zinc concentration.</p>
},
	keywords = {Animals, Biological Markers, Crassostrea, Environmental Monitoring, Metallothionein, Reactive Oxygen Species, RNA, Messenger, Superoxide Dismutase, Water Pollutants, Chemical, Zinc},
	issn = {1879-3363},
	doi = {10.1016/j.marpolbul.2012.06.017},
	author = {Mottin, E and Christelle Caplat and Latire, T and Mottier, A and M-L Mahaut and Katherine Costil and D Barillier and Jean-Marc Lebel and Antoine Serpentini}
}
