@article {9763,
	title = {Approaches and methods to study wildlife cancerAbstract},
	journal = {Journal of Animal Ecology},
	year = {2024},
	month = {Mar-08-2026},
	abstract = {The last few years have seen a surge of interest from field ecologists and evolutionary biologists to study neoplasia and cancer in wildlife. This contributes to the One Health Approach, which investigates health issues at the intersection of people, wild and domestic animals, together with their changing environments. Nonetheless, the emerging field of wildlife cancer is currently constrained by methodological limitations in detecting cancer using non-invasive sampling. In addition, the suspected differential susceptibility and resistance of species to cancer often make the choice of a unique model species difficult for field biologists.<br>
Here, we provide an overview of the importance of pursuing the study of cancer in non-model organisms and we review the currently available methods to detect, measure and quantify cancer in the wild, as well as the methodological limitations to be overcome to develop novel approaches inspired by diagnostic techniques used in human medicine.<br>
The methodology we propose here will help understand and hopefully fight this major disease by generating general knowledge about cancer, variation in its rates, tumour-suppressor mechanisms across species as well as its link to life history and physiological characters. Moreover, this is expected to provide key information about cancer in wildlife, which is a top priority due to the accelerated anthropogenic change in the past decades that might favour cancer progression in wild populations.},
	issn = {0021-8790},
	doi = {10.1111/1365-2656.14144},
	url = {https://besjournals.onlinelibrary.wiley.com/doi/10.1111/1365-2656.14144https://besjournals.onlinelibrary.wiley.com/doi/pdf/10.1111/1365-2656.14144},
	author = {Giraudeau, Mathieu and Vincze, Orsolya and Dupont, Sophie M. and Sepp, Tuul and Baines, Ciara and Lemaitre, Jean-Francois and Lemberger, Karin and Gent{\`e}s, Sophie and Boddy, Amy and Dujon, Antoine M. and Bramwell, Georgina and Harris, Valerie and Ujvari, Beata and Alix-Panabi{\`e}res, Catherine and Lair, Stephane and Sayag, David and Conde, Dalia A. and Colchero, Fernando and Harrison, Tara M. and Pavard, Samuel and Padilla-Morales, Benjamin and Chevallier, Damien and Hamede, Rodrigo and Roche, Benjamin and Malkocs, Tamas and Aktipis, Athena C. and Maley, Carlo and DeGregori, James and Le~Loc{\textquoteright}h, Guillaume and Thomas, Fr{\'e}d{\'e}ric}
}
