@article {6885,
	title = {Cg-SoxE and Cg-β-catenin, two new potential actors of the sex-determining pathway in a hermaphrodite lophotrochozoan, the Pacific oyster Crassostrea gigas},
	journal = {Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology},
	volume = {167},
	year = {2014},
	pages = {68-76},
	abstract = {Sex determination is poorly known in mollusks, lophotrochozoa and most hermaphrodites. In the oyster Crassostrea gigas, an irregular successive hermaphrodite, sex determination may occur at the end of a gametogenetic cycle to prepare the next cycle. To investigate further into these aspects we have focused on orthologs of SoxE and β-catenin, key players of the male and female gonadic differentiation respectively in mammals. Based on phylogenetic analyses, Cg-SoxE, the oyster{\textquoteright}s SoxE ortholog, is closely related to vertebrate SoxE genes while Cg-β-catenin, the oyster{\textquoteright}s β-catenin ortholog, is classified amongst lophotrochozoa. The mRNA expression measured by qPCR in the gonadic area during a gametogenetic cycle is maximal for Cg-SoxE when sex is indiscernible and for Cg-β-catenin in mature females. Both expressions are localized from early germ cells to spermatocytes and pre-vitellogenic oocytes, and potentially in somatic cells. Cg-β-catenin is also expressed in vitellogenic oocytes. These actors may be involved in early oyster gonadic differentiation, which includes sex determination. Our results enhance the understanding of sex determination in C. gigas and in mollusks and they provide additional knowledge in compared genomics of reproduction and in molecular phylogeny.},
	keywords = {Gonadic differentiation, Oyster, Sex-determining pathways, Sox9, β-catenin},
	doi = {10.1016/j.cbpa.2013.09.018},
	url = {https://hal-normandie-univ.archives-ouvertes.fr/hal-02296496},
	author = {Santerre, Christelle and Sourdaine, Pascal and Adeline, B{\'e}atrice and Anne-Sophie Martinez}
}
@article {6890,
	title = {Oyster sex determination is influenced by temperature - First clues in spat during first gonadic differentiation and gametogenesis},
	journal = {Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology},
	volume = {165},
	year = {2013},
	pages = {61-69},
	keywords = {Oyster spat, Sex determination pathway, Sex ratio, Temperature, TSD},
	doi = {10.1016/j.cbpa.2013.02.007},
	url = {https://hal-normandie-univ.archives-ouvertes.fr/hal-02296506},
	author = {Santerre, Christelle and Sourdaine, Pascal and Marc, Nicolas and Mingant, Christian and Robert, Ren{\'e} and Anne-Sophie Martinez}
}
