@article {8881,
	title = {Effects of chronic exposure of metals released from the dissolution of an aluminium galvanic anode on the Pacific oyster Crassostrea gigas},
	journal = {Aquatic Toxicology},
	volume = {Volume 249},
	year = {2022},
	abstract = {Among the anthropogenic sources releasing metallic species into the marine environment, the galvanic anode cathodic protection system (GACP) is widely used to protect submerged metallic structures from corrosion. Galvanic anodes are an alloy of metals of which the main component is aluminum or zinc. Very few studies were performed to study their potential biological effects. We investigated the chronic toxicity of an aluminum-based galvanic anode on the Pacific oyster, Crassostrea gigas. Oysters were exposed for 84 days to three concentrations of aluminum (50, 100 and 300 {\textmu}g L-1) obtained with an electrochemical experimental device simulating the dissolution of a galvanic anode. At different exposure times, we studied a battery of biomarkers of the immune system, reproductive parameters and the metabolic state of the oysters. Results demonstrated a sensitivity of oysters at the highest concentration and some biological effects were observed especially for the malondialdehyde content in the digestive gland after 84 days of exposure. In addition to these biomarkers, the bioaccumulation of the different metals composing the anode was measured in oysters{\textquoteright} tissues. Bivalves bioaccumulated more zinc than aluminum, even if aluminium was present in greater concentrations during exposures. Moreover, exposure time did not influence the bioaccumulation of aluminum in contrast to zinc.},
	keywords = {aluminium, Bioaccumulation, Biological effects, Crassostrea gigas, galvanic anode, Oyster},
	doi = {https://doi.org/10.1016/j.aquatox.2022.106223},
	author = {Alexandre Levallois and Christelle Caplat and Olivier Basuyaux and Jean-Marc Lebel and Antoine Laisney and Katherine Costil and Antoine Serpentini}
}
@article {6885,
	title = {Cg-SoxE and Cg-β-catenin, two new potential actors of the sex-determining pathway in a hermaphrodite lophotrochozoan, the Pacific oyster Crassostrea gigas},
	journal = {Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology},
	volume = {167},
	year = {2014},
	pages = {68-76},
	abstract = {Sex determination is poorly known in mollusks, lophotrochozoa and most hermaphrodites. In the oyster Crassostrea gigas, an irregular successive hermaphrodite, sex determination may occur at the end of a gametogenetic cycle to prepare the next cycle. To investigate further into these aspects we have focused on orthologs of SoxE and β-catenin, key players of the male and female gonadic differentiation respectively in mammals. Based on phylogenetic analyses, Cg-SoxE, the oyster{\textquoteright}s SoxE ortholog, is closely related to vertebrate SoxE genes while Cg-β-catenin, the oyster{\textquoteright}s β-catenin ortholog, is classified amongst lophotrochozoa. The mRNA expression measured by qPCR in the gonadic area during a gametogenetic cycle is maximal for Cg-SoxE when sex is indiscernible and for Cg-β-catenin in mature females. Both expressions are localized from early germ cells to spermatocytes and pre-vitellogenic oocytes, and potentially in somatic cells. Cg-β-catenin is also expressed in vitellogenic oocytes. These actors may be involved in early oyster gonadic differentiation, which includes sex determination. Our results enhance the understanding of sex determination in C. gigas and in mollusks and they provide additional knowledge in compared genomics of reproduction and in molecular phylogeny.},
	keywords = {Gonadic differentiation, Oyster, Sex-determining pathways, Sox9, β-catenin},
	doi = {10.1016/j.cbpa.2013.09.018},
	url = {https://hal-normandie-univ.archives-ouvertes.fr/hal-02296496},
	author = {Santerre, Christelle and Sourdaine, Pascal and Adeline, B{\'e}atrice and Anne-Sophie Martinez}
}
@article {6889,
	title = {Identification and expression of a factor of the DM family in the oyster Crassostrea gigas},
	journal = {Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology},
	volume = {152},
	year = {2009},
	pages = {189-196},
	keywords = {Crassostrea gigas, Dmrt1, Dmrt4, Dmrt5, Oyster, Sex determination},
	doi = {10.1016/j.cbpa.2008.09.019},
	url = {https://hal-normandie-univ.archives-ouvertes.fr/hal-02296545},
	author = {Naimi, Amine and Anne-Sophie Martinez and Specq, Marie-Laure and Mrac, Abdellah and Diss, Blandine and Mathieu, Michel and Sourdaine, Pascal}
}
@article {6891,
	title = {Molecular cloning and gene expression of Cg-Foxl2 during the development and the adult gametogenetic cycle in the oyster Crassostrea gigas},
	journal = {Comparative Biochemistry and Physiology - Part B: Biochemistry and Molecular Biology},
	volume = {154},
	year = {2009},
	pages = {134-142},
	keywords = {Adult gametogenetic cycle, Cg-DMl, Crassostrea gigas, Development, Foxl2, Gonad, Oyster, Sex determination},
	doi = {10.1016/j.cbpb.2009.05.011},
	url = {https://hal-normandie-univ.archives-ouvertes.fr/hal-02296548},
	author = {Naimi, Amine and Anne-Sophie Martinez and Specq, Marie-Laure and Diss, Blandine and Mathieu, Michel and Sourdaine, Pascal}
}
