EVOREG - Evolution of regulations and control of biological cycles
Our team is interested in regulations at the level of the organism, their molecular mechanisms and their role in the control, evolution and adaptation of biological life cycles. Our goal is to understand the evolution of these regulations. We use multiple approaches dealing with different organizational and temporal levels: neuroendocrine regulations in so-called “non-conventional model species”, cellular and integrative physiology of the regulatory systems, development and phylogeny of regulatory systems.
In addition to this evolutionary point of view, we also integrate as far as possible ecological and ecophysiological data relative to the life cycle of these species (eco-evo-devo / eco-evo-endocrino approaches). Such an integrated approach allows a better understanding of past biological systems and their evolution on one hand, and hopefully comes to better predictions in terms of adaptive abilities of these biological systems on the other hand.
The “non conventional” biological models we use (molluscs: oyster, cuttlefish; non-mammalian vertebrates: migratory teleost and chondrichthyan) are chosen for their phylogenetic, ecological and/or socio-economical interest.
Our approach aims at an integrated comprehension of biological functions, in their ecological context and under the light of their historical contingency.
Our main research axes are
- Neuro-hormonal control of reproduction and other key steps of biological cycles (growth, metamorphosis, migrations)
Depending on the models and the current knowledge, we are interested in
- the characterization / deorphanisation of receptors
- the characterization of the neuroendocrine pathways controlling the biological cycle
- the evolution of these neuroendocrine pathways by genomic and phylogenetic approaches.
- Development and evolution of the systems allowing the perception and analysis of ecological inputs (light, temperature, salinity, gas content), especially of the cellular and molecular actors implicated in neuronal circuitry responsible for this perception.
- Adaptive and evolutive consequences of the plasticity of these biological control systems, particularly in response to induced environmental changes (including global warming)
Latest scientific articles
2020
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. 2020. “Unravelling The Changes During Induced Vitellogenesis In Female European Eel Through Rna-Seq: What Happens To The Liver?”. Plos One 15 (8): e0236438. doi:10.1371/journal.pone.023643810. https://dx.plos.org/10.1371/journal.pone.0236438.
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. 2020. “Endocrinology: An Evolutionary Perspective On Neuroendocrine Axes In Teleosts”. In The Physiology Of Fishes, Fifth Edition, Suzanne Curie and David H. Evans, Editors, 105-116. Boca Raton,FL: CRC Press, Taylor & Francis Group. doi:10.1201/9781003036401 .
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. 2020. “Origin And Evolution Of The Neuroendocrine Control Of Reproduction In Vertebrates, With Special Focus On Genome And Gene Duplications”. Physiological Reviews 100 (2): 869 - 943. doi:10.1152/physrev.00009.2019. https://journals.physiology.org/doi/10.1152/physrev.00009.2019.
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. 2020. “How Good Is The Evidence That Light At Night Can Affect Human Health?”. Graefe's Archive For Clinical And Experimental Ophthalmology 258 (2): 231 - 232. doi:10.1007/s00417-019-04579-6. http://link.springer.com/10.1007/s00417-019-04579-6.
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. 2020. “Basal Teleosts Provide New Insights Into The Evolutionary History Of Teleost-Duplicated Aromatase”. General And Comparative Endocrinology 291: 113395. doi:10.1016/j.ygcen.2020.113395. https://linkinghub.elsevier.com/retrieve/pii/S0016648019303326.
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. 2020. “Gonadotropin-Inhibitory Hormone In Teleosts: New Insights From A Basal Representative, The Eel”. General And Comparative Endocrinology 287: 113350. doi:10.1016/j.ygcen.2019.113350. https://linkinghub.elsevier.com/retrieve/pii/S0016648019303296.
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. 2020. “Identification And Stable Expression Of Vitellogenin Receptor Through Vitellogenesis In The European Eel”. Animal 14 (6): 1213 - 1222. doi:10.1017/S1751731119003355. https://www.cambridge.org/core/product/identifier/S1751731119003355/type/journal_article.
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. 2020. “Effects Of A Temperature Rise On Atlantic Salmon, Salmo Salar, Melatonin And Thyroid Hormones During Smoltification”. Journal Of Comparative Physiology B accepted.
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. 2020. “Effects Of A Temperature Rise On Melatonin And Thyroid Hormones During Smoltification Of Atlantic Salmon, Salmo Salar”. J Comp Physiol B. doi:10.1007/s00360-020-01304-2. https://link.springer.com/article/10.1007%2Fs00360-020-01304-2.
Gallery
Team members
PhD Thesis
Programs
| 2020 to 2023 | Yuschan Schoolar Program Taiwan |
| 2020 to 2023 | Add-on Project |
| 2020 to 2023 | Yuschan Scholar Program Taiwan |
| 2020 to 2022 | APOSTD 2020 |
| 2019 to 2021 | UPSIDE |
| 2018 to 2021 | ECUME |
| 2019 to 2021 | DIM1Health |
| 2015 to 2020 | MANCHE 2012 |
| 2019 to 2020 | PHC Finlay |
| 2015 to 2019 | NEMO |
| 2017 to 2018 | ATM LOCUS |
| 2018 | JSPS 2018 LIGHTOME, France-Japon |
| 2018 | Peptides sécrétagogues de l’hormone de croissance chez les espèces d’intérêt aquacole : abord des effets neuroendocrines directs hypophysaires chez les téléostéens |
| 2015 to 2018 | IMPRESS |
| 2016 to 2017 | DEVO-LU puis LEDS |
| 2014 to 2017 | Global Networking Talent, MoST Taiwan |
| 2013 to 2017 | ANR SalTemp |
| 2014 to 2017 | REPRO-TEMP France-Espagne |
| 2013 to 2016 | COST AQUAGAMETE |
| 2011 to 2016 | Alosa alosa |
| 2015 to 2016 | ATM SEPIOM |
| 2016 | DEVEOP (Picard+) |
| 2015 to 2016 | DYNA |
| 2014 to 2015 | MADREPOP |
| 2014 to 2015 | ATM CRISPR |
| 2010 to 2015 | PRO-EEL |
| 2014 | ATM PIGMENT |
| 2014 | ATM YEUX |
| 2010 to 2014 | ANR IMMORTEEL |