EVOREG - Evolution of regulations and control of biological cycles
Our team is interested in regulations at the level of the organism, their molecular mechanisms and their role in the control, evolution and adaptation of biological life cycles. Our goal is to understand the evolution of these regulations. We use multiple approaches dealing with different organizational and temporal levels: neuroendocrine regulations in so-called “non-conventional model species”, cellular and integrative physiology of the regulatory systems, development and phylogeny of regulatory systems.
In addition to this evolutionary point of view, we also integrate as far as possible ecological and ecophysiological data relative to the life cycle of these species (eco-evo-devo / eco-evo-endocrino approaches). Such an integrated approach allows a better understanding of past biological systems and their evolution on one hand, and hopefully comes to better predictions in terms of adaptive abilities of these biological systems on the other hand.
The “non conventional” biological models we use (molluscs: oyster, cuttlefish; non-mammalian vertebrates: migratory teleost and chondrichthyan) are chosen for their phylogenetic, ecological and/or socio-economical interest.
Our approach aims at an integrated comprehension of biological functions, in their ecological context and under the light of their historical contingency.
Our main research axes are
- Neuro-hormonal control of reproduction and other key steps of biological cycles (growth, metamorphosis, migrations)
Depending on the models and the current knowledge, we are interested in
- the characterization / deorphanisation of receptors
- the characterization of the neuroendocrine pathways controlling the biological cycle
- the evolution of these neuroendocrine pathways by genomic and phylogenetic approaches.
- Development and evolution of the systems allowing the perception and analysis of ecological inputs (light, temperature, salinity, gas content), especially of the cellular and molecular actors implicated in neuronal circuitry responsible for this perception.
- Adaptive and evolutive consequences of the plasticity of these biological control systems, particularly in response to induced environmental changes (including global warming)
Latest scientific articles
2024
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. 2024. “Encyclopedia Of Reproduction. Photoperiodism In Fish”. In Encyclopedia Of Reproduction, 3rd editionrd ed. Vol. 6. Elsevier.
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. 2024. Hormones And Reproduction Of Vertebrates, Volume 1, Chapitre 9, The Pineal And Reproduction Of Teleosts And Other Fishes. Hormones And Reproduction Of Vertebrates. 2ndnd ed. Vol. 1. 5 vol. Elsevier. doi:10.1016/B978-0-443-16009-7.00008-6.
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. 2024. “The Expression Profiles Of Cyp19A1, Sf-1, Esrs And Gths In The Brain-Pituitary During Gonadal Sex Differentiation In Juvenile Japanese Eels”. General And Comparative Endocrinology 353: 114512. doi:10.1016/j.ygcen.2024.114512.
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. 2024. “The Effect Of Gonadal Hormones On The Gene Expression Of Brain-Pituitary In Protandrous Black Porgy, Acanthopagrus Schlegelii”. General And Comparative Endocrinology 351: 114482. doi:10.1016/j.ygcen.2024.114482.
2023
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. 2023. “Duplicated Paralog Of Sulfide: Quinone Oxidoreductase Contributes To The Adaptation To Hydrogen Sulfide-Rich Environment In The Hydrothermal Vent Crab, Xenograpsus Testudinatus”. Science Of The Total Environment 890: 164257. doi:10.1016/j.scitotenv.2023.164257. https://linkinghub.elsevier.com/retrieve/pii/S0048969723028784.
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. 2023. “Structural And Functional Characterization Of An Egg-Laying Hormone Signaling System In A Lophotrochozoan - The Pacific Oyster (Crassostrea Gigas).”. Gen Comp Endocrinol 346: 114417. doi:10.1016/j.ygcen.2023.114417.
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. 2023. “Comparative Proteome Analysis Of Four Stages Of Spermatogenesis In The Small-Spotted Catshark (Scyliorhinus Canicula)”. Journal Of Proteome Research 22 (7): 2477 - 2492. doi:https://doi.org/10.1021/acs.jproteome.3c00206. https://pubs.acs.org/doi/10.1021/acs.jproteome.3c00206.
2022
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. 2022. “Tachykinins, New Players In The Control Of Reproduction And Food Intake: A Comparative Review In Mammals And Teleosts”. Frontiers In Endocrinology 13. doi:10.3389/fendo.2022.1056939. https://www.frontiersin.org/articles/10.3389/fendo.2022.1056939/full.
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. 2022. “Cephalopod Palaeobiology: Evolution And Life History Of The Most Intelligent Invertebratesabstract”. Swiss Journal Of Palaeontology 141 (1). doi:10.1186/s13358-022-00247-1. https://sjpp.springeropen.com/articles/10.1186/s13358-022-00247-1.
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. 2022. “New Insights Into The Evolution Of Corticotropin-Releasing Hormone Family With A Special Focus On Teleosts”. Frontiers In Endocrinology 13: 937218. doi:Doi: 10.3389/fendo.2022.937218.
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