Following upon a project of FAPERJ/ Sorbonne Université (DYNA project), this project involves the neurogenesis from quantitative and qualitative point of view during the development of Sepia officinalis. The aim is to evaluate the dynamic during the development and after hatching to test the influence of external conditions and environmental indicators on the neurogenesis.
The neurogenesis process, during development and growth, gives organisms the capacity to increase their abilities and/or to renew cells in senescence.
Despite the extensive studies on vertebrates, this process still unexplored in non-vertebrates animals. Cephalopods have a continuous growth throughout adult life, performing complex behaviours and cognitive abilities similar to those of mammals and unique among lophotrochozoans.
These learning and locomotive behaviours are mainly led visually and controlled by the central nervous system (CNS), including the brain and the optic lobes.
Neurogenesis from quantitative and qualitative point of view during the development has yet to be established. The number of neurons in the CNS will be estimated during the development, for juvenile and adult (male and female) using the method of Isotropic fractionator. The proportion of dopaminergic neurons will be estimated to test the link between neurogenesis, maturation of CNS and cognitive abilities acquisition during the life cycle.