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Team 2: Reproduction and development of aquatic organisms: evolution, adaptation, regulations

AXE 1 : Gonade d'huître
AXE 2 : Récepteur dopaminergique dans le cerveau d’anguille

General topics

The objectives of our project is to determine molecular and physiological mechanisms underlying reproduction (differentiation, sex determination, gametogenesis and gametes emission, control of the associated metabolisms) and development (organogenesis, neurogenesis and myogenesis). This approach integrates the role of environmental factors in these regulations (epigenetic mechanisms). The genomic data and the functional approaches applied on our models (oyster, cuttlefish, dogfish, eel) constitute an advantage to reach our objectives and raise evolutionary hypotheses.

Research axes

  1. Genetic and epigenetic regulation of development and reproduction
    We study molecular mechanisms controlling development and reproduction with (at?) two )analysis) levels :
    1. genes and gene networks involved in morphological and physiological processes
    2. mechanisms responsible of gene expression

    At these two levels, environmental factors could have an impact on these processes
    The objective is to analyse, by a comparative approach, the role of these genes and their upstream regulations.

    1. the organogenesis, neurogenesis in particular that constitutes a keypoint in the adaptation of the organisms to the ecosystem;
    2. the gametogenesis and the influence of local environment (as the stem cell niche) and external to the organism (chemical or physical aquatic factors).
  2. (Neuro)hormonal control of development and reproduction
    The central nervous system, as the main integrative center of the environmental parameters coordinaes and participates to the adaptation of the physiological processes by the action of neuromodulators released near the target cells and/or secreted in circulatory system to exert an effect on distant target cells. Neuropeptides are among the main neuromodulators appeared very early in the animal evolution. The development of genomics and new sequencing technology allow the analysis of these regulatory systems by a comparative and evolutionary approach concerning several models having an economic interest and located at key position in the metazoan phylogenetic tree (Chondrichtyen : dogfish ; Teleostean : eel ; Mollusc bivalvia: oyster; and cephalopod: cuttlefish; and Cnidarian, Euphyllia).

Research Programs

Program type Complete title Schedule
Yuschan Schoolar Program Taiwan International Evolutionary endocrinology of marine organisms 2020 to 2023
HERITAGe National/Regional HERitabilité, épITranscriptome et Adaptation chez l’huître C. Gigas Effets de contaminants émergents, microplastiques et microalgues toxiques, sur le développement de l'huître via héritabilité épigénétique par méthylation de l'ARN 2019 to 2020
UPSIDE National/Regional UV effects & pigments during Sepia officinalis development 2019 to 2021
MATO National/Regional Maturité objective des poissons par l'histologie quantitative - projet politique de site IFREMER 2018 to 2019
ATM LOCUS National/Regional Première LOcalisation ChromosomiqUe de gènes du déterminisme du Sexe chez les mollusques - approche comparative chez l’huître Crassostrea gigas et la seiche Sepia officinali 2017 to 2018
Salinité huitres National/Regional Salinité - Etude de la salinité de l’eau de stockage sur la composition biochimique et la texture de la chair des huîtres ainsi que sur leurs caractéristiques organoleptiques. Convention CRBN Actions en faveur du développement économique de la filière re 2017 to 2019
DEVO-LU puis LEDS National/Regional Rôle de la lumière sur le développement du système visuel des embryons et le comportement des juvéniles de Sepia officinalis 2016 to 2017
Biligncell National/Regional Mise en place d'une lignée cellulaire de bivalve - Convention CRBN Actions en faveur du développement économique de la filière ressources marines 2016 to 2019
ATM SEPIOM National/Regional Evolution of molluscan shell : organic components involved in shell synthesis in Sepia officinalis (Cephalopod) 2015 to 2016
DYNA International Neurogenesis dynamics in the cuttlefish Sepia officinalis 2015 to 2016
BestClim National/Regional Buccin espèce sentinelle pour le climat - Convention CRBN 2015 PCM 22 Synergies Partenariale et Actions Novatrices 2015 to 2016
IMPRESS European Improved production strategies for the conservation and management of endangered freshwater fish 2015 to 2018
NEMO International Neuropeptides of Marine organisms 2015 to 2019
Buloclim National/Regional Effets des changements climatiques sur le bulot. Convention CRBN 2013 PCM 14 Synergies Partenariale et Actions Novatrices 2013 to 2014
NAISSAIN National/Regional «Study of the physiological status of oyster spat» - Convention CRBN 2013-PCM 05 Synergies Partenariales et Actions Novatrices 2013 to 2015
TRIPLOIDES National/Regional Blockade of the triploid oysters reproduction : underlying mechanism and environmental impact - Convention CRBN 2013-PCM 04 Synergies Partenariale et Actions Novatrices 2013 to 2015
OLICEB International OLICEB: OLfaction In CEphalopod Brain 2013 to 2016
ANR SalTemp National/Regional Global warming and adaptation of migration in Atlantic salmon from long river Loire-Allier Axis 2013 to 2017
K4AQUA National/Regional Antibacterial peptide K4 potential in aquaculture farms 2012 to 2014
PEPTISAN National/Regional Projet de développement de peptides thérapeutiques issus de la roussette (Scyliorhinus canicula), Région Basse-Normandie – FEDER 2890/33528 2012 to 2014
GIMEPEC National/Regional Génotoxicité immunotoxicité et repro-toxicité des pesticides chez C. gigas. ANR 11-CESA 0016 2012 to 2016
Alosa alosa European Conservation and restoration of the Allis shad in the Gironde and Rhine watersheds 2011 to 2016
ANR IMMORTEEL International IMpacts of Metallic and ORganic contaminations of the Gironde and St Laurent systems on two Threatened species, the European and American EELs 2010 to 2014
PRO-EEL European Reproduction of European eel: towards a sustained aquaculture 2010 to 2015
Eel genome project International International Consortium: The Eel genome project 2010 to 2016
REPROSEED European REsearch to improve PROduction of SEED of established and emerging bivalve species in European hatcheries, FP7 245119 2009 to 2014
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Scientific papers

Displaying 41 - 50 of 285

Moteur de recherche Bibliographie

Cornet V, Henry J, Goux D, et al. (2015) How Egg Case Proteins Can Protect Cuttlefish Offspring?. PLoS One 10:e0132836. doi: 10.1371/journal.pone.0132836
PDF icon Fontaine et al Endocrinology2015.pdf (19.93 MB)
Guo X, He Y, Zhang L, et al. (2015) Immune and Stress Responses in Oysters with Insights on Adaptation. Fish Shellfish Immunol. doi: 10.1016/j.fsi.2015.05.018
He Y, Jouaux A, Ford SE, et al. (2015) Transcriptome analysis reveals strong and complex antiviral response in a mollusc. Fish Shellfish Immunol. doi: 10.1016/j.fsi.2015.05.023
PDF icon Maugars_Dufour_2015_pone.0135184.pdf (2.39 MB)
PDF icon sawsann 2015 ruditapes.pdf (567.85 KB)
PDF icon Morini_Lafont_PLoSOne2015.pdf (1.48 MB)
PDF icon GigaTON.pdf (3.09 MB)