@article{2619,
  author = {Sophie Berland and O Delattre and Sandrine Borzeix and Y Catonne and E Lopez},
  title = {Nacre/bone interface changes in durable nacre endosseous implants in sheep},
  abstract = {Raw nacre implants persist even after 9 months of implantation into bone tissue in sheep. However the nacre surface undergoes a limited biodegradation process. Smooth-surfaced nacre implants were seen to become microporous after implantation. The results of these long-term. in vivo studies show that the overall process involves bone-resorbing cells, relies on a two-phase mechanism and may correspond to a regulation process. The rate of surface change depends on the bone implantation site and the nacre/bone interaction. The in vivo biodegradability of nacre is a highly variable parameter. The size and shape of the implanted nacre and the cellular environment of the implant are key factors in determining the biodegradation kinetics of the nacre in a living system. (C) 2004 Elsevier Ltd. All rights reserved.},
  year = {2005},
  journal = {Biomaterials},
  volume = {26},
  pages = {2767–2773},
  issn = {0142-9612},
  doi = {10.1016/j.biomaterials.2004.07.019},
  language = {eng},
}