@article{9763,
  author = {Mathieu Giraudeau and Orsolya Vincze and Sophie Dupont and Tuul Sepp and Ciara Baines and Jean-Francois Lemaitre and Karin Lemberger and Sophie Gent{\`e}s and Amy Boddy and Antoine Dujon and Georgina Bramwell and Valerie Harris and Beata Ujvari and Catherine Alix-Panabi{\`e}res and Stephane Lair and David Sayag and Dalia Conde and Fernando Colchero and Tara Harrison and Samuel Pavard and Benjamin Padilla-Morales and Damien Chevallier and Rodrigo Hamede and Benjamin Roche and Tamas Malkocs and Athena Aktipis and Carlo Maley and James DeGregori and Guillaume Le~Loc{\textquoteright}h and Fr{\'e}d{\'e}ric Thomas},
  title = {Approaches and methods to study wildlife cancerAbstract},
  abstract = {The last few years have seen a surge of interest from field ecologists and evolutionary biologists to study neoplasia and cancer in wildlife. This contributes to the One Health Approach, which investigates health issues at the intersection of people, wild and domestic animals, together with their changing environments. Nonetheless, the emerging field of wildlife cancer is currently constrained by methodological limitations in detecting cancer using non-invasive sampling. In addition, the suspected differential susceptibility and resistance of species to cancer often make the choice of a unique model species difficult for field biologists.<br>
Here, we provide an overview of the importance of pursuing the study of cancer in non-model organisms and we review the currently available methods to detect, measure and quantify cancer in the wild, as well as the methodological limitations to be overcome to develop novel approaches inspired by diagnostic techniques used in human medicine.<br>
The methodology we propose here will help understand and hopefully fight this major disease by generating general knowledge about cancer, variation in its rates, tumour-suppressor mechanisms across species as well as its link to life history and physiological characters. Moreover, this is expected to provide key information about cancer in wildlife, which is a top priority due to the accelerated anthropogenic change in the past decades that might favour cancer progression in wild populations.},
  year = {2024},
  journal = {Journal of Animal Ecology},
  month = {Mar-08-2026},
  issn = {0021-8790},
  url = {https://besjournals.onlinelibrary.wiley.com/doi/10.1111/1365-2656.14144https://besjournals.onlinelibrary.wiley.com/doi/pdf/10.1111/1365-2656.14144},
  doi = {10.1111/1365-2656.14144},
  language = {eng},
}