@article {7883,
	title = {Effects of Melatonin on Anterior Pituitary Plasticity: A Comparison Between Mammals and Teleosts},
	journal = {Frontiers in Endocrinology},
	volume = {11},
	year = {2021},
	month = {Nov-01-2021},
	abstract = {Melatonin is a key hormone involved in the photoperiodic signaling pathway. In both teleosts and mammals, melatonin produced in the pineal gland at night is released into the blood and cerebrospinal fluid, providing rhythmic information to the whole organism. Melatonin acts\&nbsp;via\&nbsp;specific receptors, allowing the synchronization of daily and annual physiological rhythms to environmental conditions. The pituitary gland, which produces several hormones involved in a variety of physiological processes such as growth, metabolism, stress and reproduction, is an important target of melatonin. Melatonin modulates pituitary cellular activities, adjusting the synthesis and release of the different pituitary hormones to the functional demands, which changes during the day, seasons and life stages. It is, however, not always clear whether melatonin acts directly or indirectly on the pituitary. Indeed, melatonin also acts both upstream, on brain centers that control the pituitary hormone production and release, as well as downstream, on the tissues targeted by the pituitary hormones, which provide positive and negative feedback to the pituitary gland. In this review, we describe the known pathways through which melatonin modulates anterior pituitary hormonal production, distinguishing indirect effects mediated by brain centers from direct effects on the anterior pituitary. We also highlight similarities and differences between teleosts and mammals, drawing attention to knowledge gaps, and suggesting aims for future research.},
	doi = {10.3389/fendo.2020.605111},
	url = {https://www.frontiersin.org/articles/10.3389/fendo.2020.605111/full},
	author = {Ciani, Elia and Haug, Trude M. and Maugars, Gersende and Weltzien, Finn-Arne and Falc{\'o}n, Jack and Fontaine, Romain}
}
@article {6018,
	title = {Functional divergence of thyrotropin beta-subunit paralogs gives new insights into salmon smoltification metamorphosis},
	journal = {Scientific Reports},
	volume = {9},
	year = {2019},
	pages = {4561},
	author = {Fleming, Mitchell S and Maugars, Gersende and Lafont, Anne-Gaelle and Rancon, Jocelyn and Fontaine, Romain and Nourizadeh-Lillabadi, Rasoul and Weltzien, Finn-Arne and Santidrian Yebra-Pimentel, Elena and Dirks, Ron and McCormick, Stephen D and Rousseau, Karine and Martin, Patrick and Sylvie Dufour}
}
@article {3773,
	title = {The Dopaminergic Neurons Controlling Anterior Pituitary Functions: Anatomy and Ontogenesis in Zebrafish.},
	journal = {Endocrinology},
	year = {2015},
	month = {2015 May 12},
	pages = {en20151091},
	abstract = {<p>Dopaminergic (DA) neurons located in the preoptico-hypothalamic region of the brain exert a major neuroendocrine control on reproduction, growth and homeostasis by regulating the secretion of anterior pituitary (or adenohypophysis) hormones. Here, using a retrograde tract tracing experiment, we identified the neurons playing this role in the zebrafish. The DA cells projecting directly to the anterior pituitary are localized in the most anteroventral part of the preoptic area, and we named them preoptico-hypophyseal DA (POHDA) neurons. During development, these neurons do not appear before 72 hours post fertilization (hpf) and are the last dopaminergic cell group to differentiate. We found that the number of neurons in this cell population continues to increase life-long, proportionally to the growth of the fish. BrdU incorporation analysis suggested that this increase is due to continuous neurogenesis and not due to a phenotypic change in already existing neurons. Finally, expression profiles of several genes (foxg1a, dlx2a and nr4a2a/b) were different in the POHDA compared to the adjacent suprachiasmatic DA neurons, suggesting that POHDA neurons develop as a distinct DA cell population in the preoptic area. This study offers some insights into the regional identity of the preoptic area and provides the first bases for future functional genetic studies on the development of DA neurons controlling anterior pituitary functions.</p>
},
	issn = {1945-7170},
	doi = {10.1210/en.2015-1091},
	author = {Fontaine, Romain and Affaticati, Pierre and Bureau, Charlotte and Colin, Ingrid and Demarque, Micha{\"e}l and Sylvie Dufour and Vernier, Philippe and Yamamoto, Kei and Pasqualini, Catherine}
}
