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Effects of chlordecone on 20-hydroxyecdysone concentration and chitobiase activity in a decapod crustacean, Macrobrachium rosenbergii

TitleEffects of chlordecone on 20-hydroxyecdysone concentration and chitobiase activity in a decapod crustacean, Macrobrachium rosenbergii
Publication TypeJournal Article
Year of Publication2016
AuthorsLafontaine, A, Gismondi, E, Boulangé-Lecomte, C, Gerraudie, P, Dodet, N, Campos, F, Lemoine, S, Lagadic, L, Thomé, J-P, Forget-Leary, J
JournalAquatic toxicology
Keywords20-Hydroxyecdysone, Chitobiase, Chlordecone, Endocrine Disruptors, Macrobrachium rosenbergii
Abstract

Chlordecone (CLD) is an organochlorine insecticide abundant in aquatic environment of the French West Indies. However, few studies have investigated its impact on freshwater invertebrates. WhereasCLD is suspected of inducingendocrine disruption,this work aimed to study the effects of environmentally relevant concentrations of CLD on the 20-hydroxyecdysone (20-HE) hormone concentration and on the chitobiase activity, both having key roles in the molting process of crustaceans. In addition, the bioaccumulation of CLD was measured in the muscle tissueof Macrobrachium rosenbergiito underline potential dose-response relationship. The results have shown that CLD was bioaccumulated in exposed organisms according to a trend to a dose-response relationship. Moreover, it was observed that CLD decreased the 20-HE concentration in exposed prawns when compared to control, whatever the duration of exposure, as well as it inhibited the chitobiase activity after 30 days of exposure. The present study indicates that CLD could interfere with molting process of M. rosenbergiiby disturbing the 20-HE concentration and the activity of chitobiase, suggesting consequences at the long term on the shrimp development. This study also confirmed that CLD could be an endocrine disruptor in decapod crustaceans, as it was already observed in vertebrates.

DOI10.1016/j.aquatox.2016.04.006