Year of Publication
2024
Journal
Cell
Volume
187
Issue
24
Date Published
Jan-11-2024
Number of Pages
6943 - 6965.e39
DOI
10.1016/j.cell.2024.10.049
URL
https://www.cell.com/cell/fulltext/S0092-8674(24)01272-8
ISSN Number
00928674
HCERES category
ACL - Articles in international or national peer-reviewed journals indexed by HCERES or in international databases
Abstract
Brown seaweeds are keystone species of coastal ecosystems, often forming extensive underwater forests, and are under considerable threat from climate change. In this study, analysis of multiple genomes has provided insights across the entire evolutionary history of this lineage, from initial emergence, through later diversification of the brown algal orders, down to microevolutionary events at the genus level. Emergence of the brown algal lineage was associated with a marked gain of new orthologous gene families, enhanced protein domain rearrangement, increased horizontal gene transfer events, and the acquisition of novel signaling molecules and key metabolic pathways, the latter notably related to biosynthesis of the alginate-based extracellular matrix, and halogen and phlorotannin biosynthesis. We show that brown algal genome diversification is tightly linked to phenotypic divergence, including changes in life cycle strategy and zoid flagellar structure. The study also showed that integration of large viral genomes has had a significant impact on brown algal genome content throughout the emergence of the lineage.
