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Aude GAUTIER

Aude GAUTIER's picture

Position

Assistant professor

Affiliation

Université de CAEN Normandie (UCN)

Email

aude.gautier@unicaen.fr

Phone

+33 2 31 56 51 64

Fax

+33 2 31 56 53 46

Localisation

Université de Caen Normandie (UCN)

Team

Team 2: Reproduction and development of aquatic organisms: evolution, adaptation, regulations

Research axis/workshop

Workshop Cell Culture
Workshop Functional Genomics
Spermatogonie GFRa1+

Research topics

The spermatogonial stem cells niche is well studied in Osteichthyes (mammals, fish…) with relatively well conserved cellular markers and regulation pathways. In contrast, these aspects are rarely documented in Chondrichthyes, the Osteichthyes sister group, whose one quarter of the species are threatened due to over-fishing. So, we chose the small spotted catshark, Scyliorhinus canicula, an abundant species on our coasts, to explore the spermatogonial stem cells regulation in sharks and to compare it to other Vertebrates. Cells of the niche are characterized at a molecular level and the in vitro maintenance of these cells allows now the functional analysis of paracrine factors involved in the spermatogonial stem cells niche.

Key words: biology of reproduction, spermatogonial stem cells, paracrines factors, small spotted catshark

The japanese oyster, Crassostrea gigas, is a well-studied species in our team due to its aquaculture interest. The comprehension of the molecular mechanisms underlying its development and various physiological processes is however limited by the lack of tools for in vivo functional analysis. We develop gene invalidation in this species by a CRISPR/Cas9 approach.

Key words: biology of development, in vivo functional analysis, japanese oyster

Teaching

Teaching activities at IBFA

In Bachelor’s degree in biology (L1-3): Animal Biology, Cellular Biology of Eukaryotes, Structure and Functioning in the Animal Kingdom

In second year of the Professional Master AQUACaen: Knowledge of the Socio-professional Environment, Fishing and Fish Breeding

University diploma: Animal experimentation applied to the Biomedical Research (aquatic animals)

Knowledge diffusion to general public

Participation in the science festival at Caen