- Membres
- Pascal FAVREL
Pascal FAVREL
Pascal FAVREL
UCN Caen
Professor
University of Caen Normandy (UCN)
EVOREG
+33 2 31 56 53 61
+ 33 2 31 56 53 46
Statutaire
General topics
Key words: Molluscs, reproduction, development, genomics, peptidomics, GPCRs, neuropeptides.
Development of transcriptomic and peptidic data as well as functional genomics tools in the oyster Crassostrea gigas. Characterization of ligand /GPCR pairs using reverse endocrinology/pharmacology assays. Study of the neuroendocrine and paracrine controls of reproduction and development in molluscs.
Teaching
Teaching activities: Comparative animal biology and physiology, Molecular and cellular biology, Evolutionary and comparative endocrinology, genomics and evolution.
Administrative responsibilities
- Director of the Faculty of Biology (Institute of Fundamental and Applied Biology) of the University of Caen Basse-Normandie. http://www.unicaen.fr/ibfa/
- Deputy Director of the Research Federative structure “ICORE” (Interaction cell-Organism-environment) of the University of Caen Basse-Normandie http://www.unicaen.fr/icore/
My Papers
2021
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Réalis-Doyelle, Emilie , Julie Schwartz, Marie-Pierre Dubos, and Pascal Favrel. 2021. “Molecular And Physiological Characterization Of A Crustacean Cardioactive Signaling System In A Lophotrochozoan - The Pacific Oyster (Crassostrea Gigas): A Role In Reproduction And Salinity Acclimation.”. J Exp Biol 224 (10). doi:10.1242/jeb.241588.
2020
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Le Franc, Lorane , Benoît Bernay, Bruno Petton, Marc Since, Pascal Favrel, and Guillaume Rivière. 2020. “A Functional M6 A‐Rna Methylation Pathway In The Oyster Crassostrea Gigas Assumes Epitranscriptomic Regulation Of Lophotrochozoan Development”. The Febs Journal. doi:10.1111/febs.15500. https://onlinelibrary.wiley.com/doi/abs/10.1111/febs.15500.febs.15500.pdf (1.47 MB)
2019
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Cherif–Feildel, Maëva , Clothilde Berthelin, Béatrice Adeline, Guillaume Rivière, Pascal Favrel, and Kristell Kellner-Cousin. 2019. “Molecular Evolution And Functional Characterisation Of Insulin Related Peptides In Molluscs: Contributions Of Crassostrea Gigas Genomic And Transcriptomic-Wide Screening”. Journal Of Comparative Endocrinology 271: 15-29.Cherif_feildel 2019.pdf (4.32 MB)
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Fellous, Alexandre , Lorane Lefranc, Aude Jouaux, Didier Goux, Pascal Favrel, and Guillaume Riviere. 2019. “Histone Methylation Participates In Gene Expression Control During The Early Development Of The Pacific Oyster .”. Genes (Basel) 10 (9). doi:10.3390/genes10090695.genes-Fellous et al.pdf (2.55 MB)
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Schwartz, Julie , Emilie Réalis-Doyelle, Marie-Pierre Dubos, Benjamin Lefranc, Jérôme Leprince, and Pascal Favrel. 2019. “Characterization Of An Evolutionarily Conserved Calcitonin Signalling System In A Lophotrochozoan, The Pacific Oyster ().”. J Exp Biol 222 (Pt 13). doi:10.1242/jeb.201319.
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Schwartz, Julie , Emilie Réalis-Doyelle, Marie-Pierre Dubos, Benjamin Lefranc, Jérôme Leprince, and Pascal Favrel. 2019. “Characterization Of An Evolutionarily Conserved Calcitonin Signalling System In A Lophotrochozoan, The Pacific Oyster (Crassostrea Gigas) ”. The Journal Of Experimental Biology 222 (13): jeb201319. doi:10.1242/jeb.201319. http://jeb.biologists.org/lookup/doi/10.1242/jeb.201319.
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Fellous, Alexandre , Lorane Le Franc, Aude Jouaux, Didier Goux, Pascal Favrel, and Guillaume Rivière. 2019. “Histone Methylation Participates In Gene Expression Control During The Early Development Of The Pacific Oyster Crassostrea Gigas”. Genes 10 (9): 695. doi:10.3390/genes10090695. https://www.mdpi.com/2073-4425/10/9/695.
2018
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Dubos, Marie-Pierre , Sven Zels, Julie Schwartz, Jeremy Pasquier, Liliane Schoofs, and Pascal Favrel. 2018. “Characterization Of A Tachykinin Signalling System In The Bivalve Mollusc Crassostrea Gigas”. General And Comparative Endocrinology 266: 110-118. doi:https://doi.org/10.1016/j.ygcen.2018.05.003.
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Schwartz, Julie , Marie-Pierre Dubos, Jeremy Pasquier, Céline Zatylny-Gaudin, and Pascal Favrel. 2018. “Emergence Of A Cholecystokinin/Sulfakinin Signalling System In Lophotrochozoa”. Scientific Reports 8: 16424. doi:doi.org/10.1038/s41598-018-34700-4. https://www.nature.com/articles/s41598-018-34700-4.CCK SK Crassostrea.pdf (3.28 MB)
2017
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Dubos, Marie-Pierre , Benoît Bernay, and Pascal Favrel. 2017. “Molecular Characterization Of An Adipokinetic Hormone-Related Neuropeptide (Akh) From A Mollusk”. General And Comparative Endocrinology 243: 15-21.
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Rivière, Guillaume , Yan He, Samuele Tecchio, Elizabeth Crowell, Michaël Gras, Pascal Sourdaine, Ximing Guo, and Pascal Favrel. 2017. “Dynamics Of Dna Methylomes Underlie Oyster Development”. Plos Genetics 13 (6): e1006807. https:// doi.org/10.13 71/journal.p gen.1006807.journal.pgen_.1006807.pdf (2.95 MB)
2015
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Rivière, Guillaume , Christophe Klopp, Nabihoudine Ibouniyamine, Arnaud Huvet, Pierre Boudry, and Pascal Favrel. 2015. “Gigaton: An Extensive Publicly Searchable Database Providing A New Reference Transcriptome In The Pacific Oyster Crassostrea Gigas.”. Bmc Bioinformatics 16: 401. doi:10.1186/s12859-015-0833-4.GigaTON.pdf (3.09 MB)
2014
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Stewart, Michael J, Pascal Favrel, Bronwyn A Rotgans, Tianfang Wang, Min Zhao, Manzar Sohail, Wayne A O'Connor, Abigail Elizur, Joël Henry, and Scott F Cummins. 2014. “Neuropeptides Encoded By The Genomes Of The Akoya Pearl Oyster Pinctata Fucata And Pacific Oyster Crassostrea Gigas: A Bioinformatic And Peptidomic Survey.”. Bmc Genomics 15: 840. doi:10.1186/1471-2164-15-840.
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Dheilly, Nolwenn M, Aude Jouaux, Pierre Boudry, Pascal Favrel, and Christophe Lelong. 2014. “Transcriptomic Profiling Of Gametogenesis In Triploid Pacific Oysters Crassostrea Gigas: Towards An Understanding Of Partial Sterility Associated With Triploidy.”. Plos One 9 (11): e112094. doi:10.1371/journal.pone.0112094.
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Zatylny-Gaudin, Céline , and Pascal Favrel. 2014. “Diversity Of The Rfamide Peptide Family In Mollusks”. Frontiers In Endocrinology 5.RFa_review2014.pdf (655.83 KB)
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Fellous, Alexandre , Pascal Favrel, Ximing Guo, and Guillaume Rivière. 2014. “The Jumonji Gene Family In Crassostrea Gigas Suggests Evolutionary Conservation Of Jmj-C Histone Demethylases Orthologues In The Oyster Gametogenesis And Development.”. Gene 538 (1): 164-75. doi:10.1016/j.gene.2013.12.016.
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Bigot, Laetitia , Isabel Beets, Marie-Pierre Dubos, Pierre Boudry, Liliane Schoofs, and Pascal Favrel. 2014. “Functional Characterization Of A Short Neuropeptide F-Related Receptor In A Lophotrochozoan, The Mollusk Crassostrea Gigas.”. J Exp Biol 217 (Pt 16): 2974-82. doi:10.1242/jeb.104067.
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Fellous, Alexandre , Pascal Favrel, and Guillaume Rivière. 2014. “Temperature Influences Histone Methylation And Mrna Expression Of The Jmj-C Histone-Demethylase Orthologues During The Early Development Of The Oyster Crassostrea Gigas.”. Mar Genomics. doi:10.1016/j.margen.2014.09.002.