- Yann BASSAGLIA
Eco-Evo-Devo approach of neuro-muscular complex in the cephalopod Sepia officinalis
Muscular development in cephalopod lead to numerous derived structures essential in the environmental relationships of the organism (e.g. locomotion), as well as its nutrition (prey capture, respiration) and reproduction (intraspecific communication). These structures, mantle, funnel and arms but also chromatophores, are derived structures specific to cephalopods.
We aim to determine the genetic control of this development by investigating the role of genes, essentially transcription factors such as the MRF, the Hand factors or the NK and Pax families, as these genes are known to be involved in myogenesis in other species. We are particularly interested in the link between neurogenesis and myogenesis during development in order to determine the gene network involved in neuro-muscular complex setting up. We also develop gene sequences analysis of these gene families in order to get insight into their structure and their evolution in lophotrochozoans.
An other axis of my research is to elucidate the development of the skin structures allowing the colored patterns of S. officinalis: these skin patterns represent a serious adaptive advantage for benthic cephalopods (benthic cuttlefish and octopus), as they are very efficient camouflage system and a rich repertoire of potential communications. We study the development of the different structures implicated in these patterns (chromatophores and iridophores), the structure of the colored elements involved in their functionality and the control of their distribution.
By a comparative approach with other molluscs, results obtained on the cuttlefish will allow a better understanding of neuro-muscular specificity of cephalopods in the evolutionary context of the loss of protective external shell.
Methods used: Histology, electron microscopy, Immunostaining, cell culture, In situ hybridization, Bio-informatic
- Cell Biology in bachelor and master cursus at the Université Paris Est Créteil-Val de Marne (UPEC) and Université Paris Diderot (Paris 7)
- Tissular biology and histology in bachelor cursus (UPEC)
- Ecophysiology in master cursus (UPEC/Paris7)
- Zoology in field sessions in master cursus (UPEC/Paris7)
Teaching charges :
- In charge of 2 bachelor courses and 4 master courses
- Head of the master "MEEF (Métier de l'enseignement, de l'éducation et de la formation) 2nd degré SVT" (UPEC-P7). This master allows students to take the competitive exam recruting teachers in biology/geology for secondary-school (CAPES).
- Head of the "préparation à l'Agrégation interne de SVT", an adult continuing education for biology/geology teachers which allow them to take the Agrégation, a competitive examination for higher posts in France's education system.
Administrative charges :
- Vice-head of faculty for pedagogy at the Sciences and Technology faculty (UPEC)
- Elected at Sciences and Technology faculty council (UPEC)
- Member of selection commitees for UPEC, university Paris Orsay, University of Caen-Basse Normandie, Ecole Normale Supérieure de Cachan.
Navet, Sandra , Auxane Buresi, Sébastien Baratte, Aude Andouche, Laure Bonnaud-Ponticelli, and Yann Bassaglia. 2017. “The Pax Gene Family: Highlights From Cephalopods”. Plos One 12 (3): e0172719. doi:10.1371/journal.pone.017271910.1371. https://dx.plos.org/10.1371/journal.pone.0172719.
Imarazen, Boudjema , Aude Andouche, Yann Bassaglia, Pascal Jean Lopez, and Laure Bonnaud-Ponticelli. 2017. “Eye Development In Sepia Officinalis Embryo: What The Uncommon Gene Expression Profiles Tell Us About Eye Evolution”. Front. Physiol.. doi:10.3389/fphys.2017.00613.
Buresi, Auxane , Aude Andouche, S Navet, Yann Bassaglia, Laure Bonnaud-Ponticelli, and Sébastien Baratte. 2016. “Nervous System Development In Cephalopods: How Egg Yolk-Richness Modifies The Topology Of The Mediolateral Patterning System.”. Dev Biol 415 (1): 143-56. doi:10.1016/j.ydbio.2016.04.027.
Andouche, Aude , and Yann Bassaglia. 2016. “Coleoid Cephalopod Color Patterns: Adult Skin Structures And Their Emergence During Development In Sepia Officinalis”. Vie Et Milieu 66 (1): 43-55.
Bouteau, Francois , Yann Bassaglia, Emanuela Monetti, Daniel Tran, S Navet, Stefano Mancuso, Hayat El-Maarouf-Bouteau, and Laure Bonnaud-Ponticelli. 2014. “Could Farp-Like Peptides Participate In Regulation Of Hyperosmotic Stress Responses In Plants?”. Front Endocrinol (Lausanne) 5: 132. doi:10.3389/fendo.2014.00132.
Bonnaud-Ponticelli, Laure , and Yann Bassaglia. 2014. “Cephalopod Development: What We Can Learn From Differences”. Oa Biology 2 (1): 6. http://www.oapublishinglondon.com/oa-biology.
Navet, S , Sébastien Baratte, Yann Bassaglia, Aude Andouche, Auxane Buresi, and Laure Bonnaud-Ponticelli. 2014. “Neurogenesis In Cephalopods: “Eco-Evo-Devo” Approach In The Cuttlefish Sepia Officinalis (Mollusca-Cephalopoda)”. Journal Of Marine Science And Technology, Taiwan 22 (1): 15-24.