Approaches and methods to study wildlife cancerAbstract

TitreApproaches and methods to study wildlife cancerAbstract
Type de publicationJournal Article
Year of Publication2024
AuteursGiraudeau, M, Vincze, O, Dupont, SM, Sepp, T, Baines, C, Lemaitre, J‐F, Lemberger, K, Gentès, S, Boddy, A, Dujon, AM, Bramwell, G, Harris, V, Ujvari, B, Alix‐Panabières, C, Lair, S, Sayag, D, Conde, DA, Colchero, F, Harrison, TM, Pavard, S, Padilla‐Morales, B, Chevallier, D, Hamede, R, Roche, B, Malkocs, T, Aktipis, AC, Maley, C, DeGregori, J, Le Loc’h, G, Thomas, F
JournalJournal of Animal Ecology
Date PublishedMar-08-2026
ISSN0021-8790
Résumé

The last few years have seen a surge of interest from field ecologists and evolutionary biologists to study neoplasia and cancer in wildlife. This contributes to the One Health Approach, which investigates health issues at the intersection of people, wild and domestic animals, together with their changing environments. Nonetheless, the emerging field of wildlife cancer is currently constrained by methodological limitations in detecting cancer using non-invasive sampling. In addition, the suspected differential susceptibility and resistance of species to cancer often make the choice of a unique model species difficult for field biologists.

Here, we provide an overview of the importance of pursuing the study of cancer in non-model organisms and we review the currently available methods to detect, measure and quantify cancer in the wild, as well as the methodological limitations to be overcome to develop novel approaches inspired by diagnostic techniques used in human medicine.

The methodology we propose here will help understand and hopefully fight this major disease by generating general knowledge about cancer, variation in its rates, tumour-suppressor mechanisms across species as well as its link to life history and physiological characters. Moreover, this is expected to provide key information about cancer in wildlife, which is a top priority due to the accelerated anthropogenic change in the past decades that might favour cancer progression in wild populations.

URLhttps://besjournals.onlinelibrary.wiley.com/doi/10.1111/1365-2656.14144https://besjournals.onlinelibrary.wiley.com/doi/pdf/10.1111/1365-2656.14144
DOI10.1111/1365-2656.14144
Short TitleJournal of Animal Ecology
Catégorie HCERES
ACL - Articles dans des revues à comité de lecture
Publication coopération et recherche SUD
Non