PEPTRAQ

New high-throughput sequencing technologies allow for the sequencing, assembly, and annotation of transcriptomes and/or genomes regardless of the organism of origin. However, in so-called "unconventional" animal models and more particularly invertebrates, in silico analysis of the data remains tedious for lack of sufficient functional annotations and adapted computer tools. The PEPTRAQ software tool was developed by both biologists and computer scientists of the Normandy University of Caen (France) to improve these in silico analyses.

This software tool searches databases for specific data on the basis of multiple criteria such as transcript, protein precursor, protein or peptide length, peptide hydrophobicity, occurrence of a signal peptide, conserved subsequences, amino acid patterns, etc.

PEPTRAQ has to be considered as a tool dedicated to the investigation of available genomic, transcriptomic, and proteomic databases issued from conventional and unconventional models such as cephalopods. Also designed to translate and re-annotate databases, PEPTRAQ is a multipurpose and user-friendly software tool that allows users to create personalized workflows adapted to answer most of the questions in the field of data mining.

As PEPTRAQ saves filtered data in fasta files, it is a powerful tool that generates targeted and reduced databases for mass spectrometry analysis in peptidomic or proteomic approaches.

This project aims to make this software accessible.

Programme émergent régional

Funding: Conseil Régional Normandie